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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GON4L
All Species:
4.55
Human Site:
T250
Identified Species:
12.5
UniProt:
Q3T8J9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q3T8J9
NP_001032622.1
2241
248620
T250
R
R
K
K
K
K
G
T
K
R
K
R
D
G
R
Chimpanzee
Pan troglodytes
XP_513864
2206
244897
T250
R
R
K
K
K
K
G
T
K
R
K
R
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001113298
745
82419
Dog
Lupus familis
XP_547544
2226
243395
K254
R
R
K
R
K
G
S
K
R
K
R
D
A
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB00
2260
248779
K251
K
K
T
K
K
G
T
K
R
K
R
D
G
K
G
Rat
Rattus norvegicus
Q535K8
2256
247884
K250
K
K
T
K
K
G
T
K
R
K
R
D
G
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422861
2220
245918
A239
V
V
A
M
M
K
A
A
I
S
E
T
E
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922693
2055
228412
A240
N
I
S
P
I
K
K
A
N
D
I
K
P
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783309
2553
279963
R328
Q
R
K
V
M
P
V
R
R
V
V
Q
E
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
27.4
80
N.A.
74.7
75
N.A.
N.A.
60.3
N.A.
38.1
N.A.
N.A.
N.A.
N.A.
21.6
Protein Similarity:
100
97.9
30.2
86.1
N.A.
84.3
84.4
N.A.
N.A.
72.5
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
38.5
P-Site Identity:
100
100
0
26.6
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
0
53.3
N.A.
46.6
46.6
N.A.
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
12
23
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
34
23
12
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
23
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
34
23
0
0
0
0
0
23
23
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
12
0
0
0
12
0
12
0
0
0
12
% I
% Lys:
23
23
45
45
56
45
12
34
23
34
23
12
0
12
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
23
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
12
0
0
0
0
0
0
12
12
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% Q
% Arg:
34
45
0
12
0
0
0
12
45
23
34
23
0
23
23
% R
% Ser:
0
0
12
0
0
0
12
0
0
12
0
0
0
0
0
% S
% Thr:
0
0
23
0
0
0
23
23
0
0
0
12
0
0
0
% T
% Val:
12
12
0
12
0
0
12
0
0
12
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _